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ASTHMA AND COPD: MECHANISM OF ACTION OF GLUCOCORTICOIDS, β2-AGONISTS AND THEIR COMBINATION
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Introduction
 
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Combination Therapy With LABAs and ICSs: Scientific Rationale
 
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Combination Therapy With LABAs and ICSs: Scientific Rationale
Combination Therapy With LABAs and ICSs: Scientific Rationale

Many studies have demonstrated the clinical benefits of combining a LABA and an ICS both in asthma and COPD and this has led to the development of fixed combination inhalers containing a LABA and an ICS in the same device (LABACS).7

The increased efficacy of the combined administration of a LABA and an ICS is the final clinical effect of the mutual interaction that the two classes have at pathophysiological (particularly in asthma) and molecular levels (asthma and COPD).

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