This course focuses on the principles and practice of clinical epidemiology, and elaborates on examples from relevant literature. The aim is to provide you with the knowledge to evaluate and assess applied clinical research and data analyses, and give you sufficient scientific and methodological background information to actively participate in clinical studies. During the course, you will focus on questions of diagnosis, prognosis, treatment and etiology. Several research options are available to help you address these questions, including intervention trials and case-control studies using data obtained in a clinical setting.
By the end of the course, you should be able to: - Define, explain and apply the basic terminology and principles specific to clinical epidemiology - Differentiate between the different aspects of clinical epidemiological research (diagnostic / etiologic / prognostic / therapeutic) - In particular, you should be able to: - Construct a clinical research question that includes outcome, determinants and domain - Characterize different data collection designs used in clinical epidemiology - Design a clinical epidemiological study - Name and identify the data analysis techniques that are used for the different types of clinical epidemiological studies - Interpret the basic data analysis results of a clinical epidemiological study - Explain the concepts of bias, and the issues concerning confounding bias - Read and explain clinical epidemiological scientific papers and identify, in these papers, which design of data collection and data analysis were used